USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: ZYX_HUMAN USC-OGP 2-DE database:  ZYX_HUMAN ZYX_HUMAN General information about the entry View entry in simple text format Entry name ZYX_HUMAN Primary accession number Q15942 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Zyxin; AltName: Full=Zyxin-2;. Gene name Name=ZYX Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0097: pI=4.59; Mw=40926 SPOT OGP-0098: pI=4.63; Mw=40719 SPOT OGP-0101: pI=4.83; Mw=39801 SPOT OGP-0105: pI=4.65; Mw=38707 SPOT OGP-0106: pI=4.94; Mw=38707 PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0301: pI=5.85; Mw=74882 SPOT OGP-0302: pI=5.81; Mw=74421 SPOT OGP-0303: pI=5.93; Mw=74421 SPOT OGP-0305: pI=5.98; Mw=74192 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0625: pI=5.76; Mw=73886 SPOT OGP-0626: pI=5.87; Mw=73886 SPOT OGP-0627: pI=5.94; Mw=73670 SPOT OGP-0628: pI=5.92; Mw=73455 PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0861: pI=6.31; Mw=67656 SPOT OGP-0862: pI=6.16; Mw=67292 SPOT OGP-0863: pI=6.06; Mw=66930 SPOT OGP-0864: pI=5.96; Mw=66750 SPOT OGP-0865: pI=5.63; Mw=66570 SPOT OGP-0875: pI=5.95; Mw=63415 SPOT OGP-0876: pI=6.16; Mw=63415 SPOT OGP-0877: pI=6.05; Mw=63244 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1120: pI=6.09; Mw=84978 SPOT OGP-1122: pI=6.30; Mw=81577 SPOT OGP-1126: pI=6.49; Mw=74034 SPOT OGP-1135: pI=5.94; Mw=63519 SPOT OGP-1149: pI=6.17; Mw=55186 Cross-references UniProtKB/Swiss-Prot Q15942; ZYX_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name ZYX_HUMAN Primary accession number Q15942 Secondary accession number(s) A4D2G6 B4DQX7 Q6I9S4 Sequence was last modified on  November 1, 1997 (version 1) Annotations were last modified on  March 15, 2017 (version 167) Name and origin of the protein Description RecName: Full=Zyxin; AltName: Full=Zyxin-2; Gene name Name=ZYX Encoded on Name=ZYX Keywords Acetylation; Alternative splicing; Cell adhesion; Cell junction; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Host-virus interaction; LIM domain; Metal-binding; Methylation; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Zinc. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X94991; CAA64447.1; -; mRNA EMBL X95735; CAA65050.1; -; mRNA EMBL AK299005; BAG61089.1; -; mRNA EMBL AK316227; BAH14598.1; -; mRNA EMBL CR457431; CAG33712.1; -; mRNA EMBL AC092214; AAS07459.1; -; Genomic_DNA EMBL CH236959; EAL23788.1; -; Genomic_DNA EMBL CH471198; EAW51848.1; -; Genomic_DNA EMBL BC008743; AAH08743.1; -; mRNA EMBL BC009360; AAH09360.1; -; mRNA EMBL BC010031; AAH10031.1; -; mRNA CCDS CCDS5883.1; -. [Q15942-1]; . PIR G02845; G02845; . RefSeq NP_001010972.1; NM_001010972.1. [Q15942-1]; . RefSeq NP_003452.1; NM_003461.4. [Q15942-1]; . UniGene Hs.490415; -; . ProteinModelPortal Q15942; -; . SMR Q15942; -; . BioGrid 113569; 93; . IntAct Q15942; 66; . MINT MINT-220515; -; . STRING 9606.ENSP00000324422; -; . iPTMnet Q15942; -; . PhosphoSitePlus Q15942; -; . SwissPalm Q15942; -; . BioMuta ZYX; -; . DMDM 2497677; -; . OGP Q15942; -; . EPD Q15942; -; . MaxQB Q15942; -; . PaxDb Q15942; -; . PeptideAtlas Q15942; -; . PRIDE Q15942; -; . DNASU 7791; -; . Ensembl ENST00000322764; ENSP00000324422; ENSG00000159840. [Q15942-1]; . Ensembl ENST00000392910; ENSP00000376642; ENSG00000159840. [Q15942-2]; . GeneID 7791; -; . KEGG hsa:7791; -; . UCSC uc003wcx.5; human. [Q15942-1]; . CTD 7791; -; . DisGeNET 7791; -; . GeneCards ZYX; -; . HGNC HGNC:13200; ZYX; . HPA CAB009321; -; . HPA CAB075747; -; . HPA HPA004835; -; . HPA HPA073497; -; . MIM 602002; gene; . neXtProt NX_Q15942; -; . OpenTargets ENSG00000159840; -; . PharmGKB PA37765; -; . eggNOG KOG1701; Eukaryota; . eggNOG ENOG410Y3GP; LUCA; . GeneTree ENSGT00760000119039; -; . HOGENOM HOG000220910; -; . HOVERGEN HBG093602; -; . InParanoid Q15942; -; . KO K06273; -; . OMA PITERML; -; . OrthoDB EOG091G085F; -; . PhylomeDB Q15942; -; . TreeFam TF320310; -; . SIGNOR Q15942; -; . ChiTaRS ZYX; human; . GeneWiki Zyxin; -; . GenomeRNAi 7791; -; . PMAP-CutDB Q15942; -; . PRO PR:Q15942; -; . Proteomes UP000005640; Chromosome 7; . Bgee ENSG00000159840; -; . CleanEx HS_ZYX; -; . ExpressionAtlas Q15942; baseline and differential; . Genevisible Q15942; HS; . GO GO:0005913; C:cell-cell adherens junction; IDA:MGI; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0005887; C:integral component of plasma membrane; TAS:ProtInc; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; TAS:ProtInc; . GO GO:0001725; C:stress fiber; IDA:UniProtKB; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0008270; F:zinc ion binding; IEA:InterPro; . GO GO:0007155; P:cell adhesion; TAS:ProtInc; . GO GO:0007267; P:cell-cell signaling; TAS:ProtInc; . GO GO:0007160; P:cell-matrix adhesion; IC:UniProtKB; . GO GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB; . GO GO:0050727; P:regulation of inflammatory response; IEA:Ensembl; . GO GO:0007165; P:signal transduction; TAS:ProtInc; . GO GO:0043149; P:stress fiber assembly; IMP:UniProtKB; . GO GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB; . GO GO:0016032; P:viral process; IEA:UniProtKB-KW; . Gene3D 2.10.110.10; -; 3; . InterPro IPR001781; Znf_LIM; . Pfam PF00412; LIM; 3; . SMART SM00132; LIM; 3; . PROSITE PS00478; LIM_DOMAIN_1; 2; . PROSITE PS50023; LIM_DOMAIN_2; 3; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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